This is a very interesting and bold design. Skull is a major symbol of mortality and death. And this design emphasized that meaning. The design looks like a separated part of a much bigger picture of Grim Reaper.
That personification of death as a force is widely spread among the Western culture. The Grim Reaper causes the victims death by comping to collect that person.
For the wearer, this tattoo can be a sign that he has no fear of death.